60 million people worldwide are carriers of a genetic mutation, which almost inevitably lead to the development of their heart disease
Such a study published in the journal Nature Genetics.
For the first time scientists have discovered a gene mutation responsible for protein production MYBPC3 (it is contained exclusively in heart tissue), five years ago in two Indian families whose members suffered from cardiomyopathy - a disease that leads to the defeat of the heart muscle.
To conduct a larger study involved 800 patients were suffering from heart disease in the control group included 700 volunteers. His results showed that the genetic mutation of this kind is common and is observed in approximately one hundredth of each person.
The risk of developing diseases related to the cardiovascular system, the mutant gene carriers jump seven times, which means almost inevitable occurrence of the disease.
In the lab, the researchers demonstrated that heart cells that bear a mutation, which falls 25 letters of genetic code that produces a defective protein MYBPC3, which violates the structure of the heart muscle.
According to scientists, people younger organism successfully coped with the "breakdown" and restore the correct protein structure. However, in adulthood, this mechanism starts getting worse, which leads to the development of cardiovascular disease, transmit medicinews.ru.
Chris Tyler-Smith, a member of the British Institute Wellcome Trust Sanger Institute believes that this genetic mutation occurred about 30,000 years ago.
According to him, it is easy to test young people for the presence of mutations. But the problem is that effective methods of treatment has yet been found, and all that the doctor may suggest a mutant gene carriers - is to lead a healthy lifestyle.
Such a study published in the journal Nature Genetics.
For the first time scientists have discovered a gene mutation responsible for protein production MYBPC3 (it is contained exclusively in heart tissue), five years ago in two Indian families whose members suffered from cardiomyopathy - a disease that leads to the defeat of the heart muscle.
To conduct a larger study involved 800 patients were suffering from heart disease in the control group included 700 volunteers. His results showed that the genetic mutation of this kind is common and is observed in approximately one hundredth of each person.
The risk of developing diseases related to the cardiovascular system, the mutant gene carriers jump seven times, which means almost inevitable occurrence of the disease.
In the lab, the researchers demonstrated that heart cells that bear a mutation, which falls 25 letters of genetic code that produces a defective protein MYBPC3, which violates the structure of the heart muscle.
According to scientists, people younger organism successfully coped with the "breakdown" and restore the correct protein structure. However, in adulthood, this mechanism starts getting worse, which leads to the development of cardiovascular disease, transmit medicinews.ru.
Chris Tyler-Smith, a member of the British Institute Wellcome Trust Sanger Institute believes that this genetic mutation occurred about 30,000 years ago.
According to him, it is easy to test young people for the presence of mutations. But the problem is that effective methods of treatment has yet been found, and all that the doctor may suggest a mutant gene carriers - is to lead a healthy lifestyle.
