Wednesday, December 1, 2010

Gene aging brain


Canadian scientists have made a big step towards opening the treatment of neurological diseases and drug development, which retards the aging brain

They found a gene that controls normal and pathological aging of neurons in the central nervous system - Bmi1. Mutation of this gene greatly accelerates the process of disintegration of the neuronal in the brain and loss of nerve cells in their eyes.

Laboratory tests on mice showed that neurons in the retina and cerebral cortex are functioning properly is at work found gene Bmi1.

This gene also prevents the activation of the p53 path and accumulation of free radicals, leading to the advancement of brain disorders, transmit medicinews.ru.
Major risk factor for diseases such as macular degeneration, Parkinson's disease and Alzheimer's disease is old age.

Geneticists have shown that Bmi1 is a direct regulator of cell aging brain and eye retina due to its protective properties against harmful free radicals.
Doctors hope that in the future be able to unravel the genome coding for damaged neurons.

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